Bovine respiratory disease (BRD) remains a leading cause of economic losses, hampered animal welfare and antimicrobial use. The use of acute phase proteins (APPs), such as serum amyloid A (SAA) and haptoglobin (Hp), has been explored for the detection of BRD, as defined by clinical signs. However, whether these APPs are also associated with lung consolidation, as determined by thoracic ultrasonography, and have the potential to differentiate causative pathogens is unknown. Therefore, the primary objective of this study was to explore the association between lung consolidation and SAA and Hp. The second objective was to determine the ability of both SAA and Hp to differentiate pathogen groups (Mycoplasmopsis bovis, viruses and Pasteurellaceae).

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